Cholesterol-Lowering Potentials of Lactic Acid Bacteria Based on Bile-Salt Hydrolase Activity and Effect of Potent Strains on Cholesterol Metabolism In Vitro and In Vivo
Table 1
Screening of the bile salt hydrolase (BSH) activity of probiotics using the plate assay method.
Strain
MRS agar
MRS agar (0.5% TDCA)
MRS agar (0.5% TCA)
Precipitation zone diameter (mm)a
NBHK001
10 ± 1
—b
19 ± 4
NBHK002
10 ± 1
19 ± 4
16 ± 2
NBHK003
11 ± 1
12 ± 1
18 ± 3
NBHK004
10 ± 1
23 ± 4
15 ± 4
NBHK005
11 ± 1
14 ± 0
19 ± 2
NBHK006
9 ± 1
14 ± 3
20 ± 4
NBHK007
13 ± 3
24 ± 4
18 ± 2
NBHK008
9 ± 1
20 ± 4
20 ± 1
LGA-01
11 ± 1
—
16 ± 1
LRE-01
11 ± 0
17 ± 0
—
Bgal-1
11 ± 1
19 ± 0
12 ± 0
TS 111
11 ± 0
16 ± 0
13 ± 0
TS 159
11 ± 0
15 ± 0
14 ± 0
TS 6
11 ± 0
14 ± 0
11 ± 0
TS 17
12 ± 0
17 ± 0
16 ± 0
TS 18
11 ± 1
17 ± 0
16 ± 1
TS 26
11 ± 1
17 ± 0
16 ± 0
TS 29
11 ± 1
16 ± 0
18 ± 4
TS 32
13 ± 0
19 ± 0
—
RY11-M2
10 ± 1
16 ± 0
—
MY22-M1
9 ± 1
13 ± 4
—
RY11-R1
14 ± 6
16 ± 3
—
Diameter of precipitation zone included 6 mm diameter of the sterile filter disk.
bNot detected.
