Lymphocyte Oxidative Stress/Genotoxic Effects Are Related to Serum IgG and IgA Levels in Coke Oven Workers
Table 1
Demographic characteristics of workers in the control and exposed groups.
Variables
Control group (78)
Exposed group (126)
value
1-OHP (mol/mol creatine)
0.55 ± 0.28
9.36 ± 2.14***
<0.001a
Age (year)
32.4 ± 4.9
33.6 ± 5.2
0.103a
Employment time (year)
12.7 ± 2.5
14.1 ± 2.7***
<0.001a
Current smokers, yes (%)
41 (52.6%)
79 (62.7%)
0.153b
Alcohol users, yes (%)
18 (23.1%)
57 (45.2%)
0.001b
MDA (nmol/mL)
1.23 ± 0.37
1.97 ± 0.61***
<0.001a
8-OH-dG (nmol/mol creatinine)
1.29 ± 0.15
2.20 ± 0.19***
<0.001a
CTL (m)
3.16 ± 0.58
7.49 ± 0.89***
<0.001a
CTM
0.85 ± 0.23
10.48 ± 3.52***
<0.001a
MN ()
1.83 ± 0.51
2.78 ± 0.63***
<0.001a
CA (N, AR%)
10, 12.8%
36, 28.6%
0.009b
IgG (g/L)
0.36 ± 0.11
0.12 ± 0.03***
<0.001a
IgA (g/L)
2.09 ± 0.44
1.66 ± 0.44***
<0.001a
IgM (g/L)
1.76 ± 0.69
1.62 ± 0.72
0.172a
IgE (IU/mL)
173.90 ± 30.24
167.76 ± 43.16
0.273a
1-OHP: 1-hydroxypyrene; CTL: comet tail length; CTM: comet tail moment; MN: micronucleus; CA: chromosomal aberrations. Values are shown mean ± SD except where indicated. awhen compared with control by Mann-Whitney test, bwhen compared with control by chi-square test. .