Research Article

Lymphocyte Oxidative Stress/Genotoxic Effects Are Related to Serum IgG and IgA Levels in Coke Oven Workers

Table 1

Demographic characteristics of workers in the control and exposed groups.

VariablesControl group (78)Exposed group (126) value

1-OHP ( mol/mol creatine)0.55 ± 0.289.36 ± 2.14***<0.001a
Age (year)32.4 ± 4.933.6 ± 5.20.103a
Employment time (year)12.7 ± 2.514.1 ± 2.7***<0.001a
Current smokers, yes (%)41 (52.6%)79 (62.7%)0.153b
Alcohol users, yes (%)18 (23.1%)57 (45.2%)0.001b
MDA (nmol/mL)1.23 ± 0.371.97 ± 0.61***<0.001a
8-OH-dG (nmol/mol creatinine)1.29 ± 0.152.20 ± 0.19***<0.001a
CTL ( m)3.16 ± 0.587.49 ± 0.89***<0.001a
CTM0.85 ± 0.2310.48 ± 3.52***<0.001a
MN ( )1.83 ± 0.512.78 ± 0.63***<0.001a
CA (N, AR%)10, 12.8%36, 28.6%0.009b
IgG (g/L)0.36 ± 0.110.12 ± 0.03***<0.001a
IgA (g/L)2.09 ± 0.441.66 ± 0.44***<0.001a
IgM (g/L)1.76 ± 0.691.62 ± 0.720.172a
IgE (IU/mL)173.90 ± 30.24167.76 ± 43.160.273a

1-OHP: 1-hydroxypyrene; CTL: comet tail length; CTM: comet tail moment; MN: micronucleus; CA: chromosomal aberrations. Values are shown mean ± SD except where indicated. awhen compared with control by Mann-Whitney test, bwhen compared with control by chi-square test.
.