The Influence of pH and Temperature on the Stability of <i>N</i>-[(Piperidine)methylene]daunorubicin Hydrochloride and a Comparison of the Stability of Daunorubicin and Its Four New Amidine Derivatives in Aqueous Solutions

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</svg>(pH) profiles of daunorubicin (DAU) and its four amidine derivatives: <i>N</i>-[(pyrrolidine)methylene]daunorubicin (PMD), <i>N</i>-[(morpholine) methylene]daunorubicin (MMD), <i>N</i>-[(piperidine) methylene]daunorubicin (PPD), and <i>N</i>-[(hexahydroazepin-1yl) methylene]daunorubicin (HMD) in aqueous solutions at 313 K.</table>

The Scientific World Journal

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Figure 6

Figure 6: The Influence of pH and Temperature on the Stability of <i>N</i>-[(Piperidine)methylene]daunorubicin Hydrochloride and a Comparison of the Stability of Daunorubicin and Its Four New Amidine Derivatives in Aqueous Solutions 

Figure 6 | The Influence of pH and Temperature on the Stability of N-[(Piperidine)methylene]daunorubicin Hydrochloride and a Comparison of the Stability of Daunorubicin and Its Four New Amidine Derivatives in Aqueous Solutions 