Caloric Restriction Prevents Lead-Induced Oxidative Stress and Inflammation in Rat Liver
Liver superoxide dismutase (SOD) in ad libitum (AL) and caloric restriction (CR) groups after lead or saline administrations. Seven days of lead injections (15 mg/Kg body weight, ip) to AL animals caused significant reduction of liver SOD (* compared to the saline-injected AL); in CR animals SOD changes after the same dose lead administration were not significant. Liver SOD content was significantly higher in lead-administered CR compared to lead-administered AL (# compared to the lead-injected AL). The data are presented as means ± SEM.