Table of Contents Author Guidelines Submit a Manuscript
The Scientific World Journal
Volume 2014, Article ID 834931, 6 pages
Review Article

Brain AVMs: An Endovascular, Surgical, and Radiosurgical Update

1Department of Neurology and Psychiatry, Endovascular Neurosurgery/Interventional Neuroradiology, “Sapienza” University of Rome, Viale del Policlinico 155, 00100 Rome, Italy
2Department of Neurology and Psychiatry, Neurosurgery, “Sapienza” University of Rome, Rome, Italy
3Department of Neurology and Psychiatry, Neuroradiology, “Sapienza” University of Rome, Italy
4Department of Neurology and Psychiatry, Interventional Neuroradiology, “Sapienza” University of Rome, Italy

Received 12 June 2014; Accepted 1 August 2014; Published 21 October 2014

Academic Editor: Robert M. Starke

Copyright © 2014 Simone Peschillo et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Brain arteriovenous malformations (bAVMs) are complex vascular lesions. Despite multiple studies, several classifications, and a great interest of the scientific community, case selection in AVM patients remains challenging. During the last few years, tremendous advancements widened therapeutic options and improved outcomes spreading indications for patients harboring lesions deemed inoperable in the past. Anatomical and biological case specific features, and natural history with a focus on presenting symptoms should be evaluated case by case and always kept in mind while planning a therapeutic management for a bAVMs. A multidisciplinary approach is strongly recommended when dealing with bAVMs and should involve physicians expertise in this kind of challenging lesions. The goal of this paper is to provide a focused review of the most recent acquisitions and therapeutic strategies regarding surgical, endovascular, and radiosurgical treatment.