The Scientific World Journal / 2014 / Article / Tab 4

Research Article

Nanospray Drying as a Novel Technique for the Manufacturing of Inhalable NSAID Powders

Table 4

Aerodynamic properties of Klys/leu powders sprayed through a surfactant treated nozzle (70°C, 4 µm nozzle, and 6% w/v feed) after ACI experiments: emitted dose (ED), mass median aerodynamic diameter (MMAD), fine particles fraction (FPF), and fine particle dose (FPD).

BatchLeu concentration (% w/w)Water/IPA (% v/v)Emitted dose (%)MMAD (µm)FPF (%)FPD (mg)

#5d10%70/3098.4 ± 2.94.25 ± 0.1254.4 ± 0.315.8 ± 0.4
#1015%100/0100.1 ± 0.14.02 ± 0.0554.8 ± 1.118.2 ± 0.7
#1115%90/1099.7 ± 0.33.83 ± 0.0260.9 ± 1.218.0 ± 0.4
#1215%80/2099.9 ± 0.24.19 ± 0.2055.3 ± 2.516.6 ± 1.1
#1310%90/10100.8 ± 0.14.31 ± 0.2249.9 ± 3.215.5 ± 0.9

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