Validation of a Spanish Version of the Lille Apathy Rating Scale for Parkinson’s Disease

Table 1

Demographic and clinical characteristics of PD patients and healthy controls.

	PD patients; ()	Healthy controls; ()
Age (years), mean ± SD	71.6 ± 8.1	69.4 ± 8.7
Gender, male/female	78/52	39/31
Education level, (%)
No studies	15 (11.5)	13 (18.6)
Primary	82 (63.1)	38 (54.3)
Secondary	25 (19.2)	12 (17.1)
High	8 (6.2)	7 (10.0)
Duration of disease, median months (range)	49 (26.8–113.2)
Hoenh and Yahr scale, (%)
Stage I	34 (26.2)
Stage II	72 (55.4)
Stage III	21 (16.2)
Stage IV	2 (1.5)
Stage V	1 (0.8)
UPDRS score, mean ± SD
Part I	2.9 ± 2.3
Part II	7.8 ± 5.7
Part III	22.9 ± 10.9
Part IV	1.6 ± 3.2
MEC score, mean ± SD	30.7 ± 3.8	33.3 ± 1.7*
MADRS score, mean ± SD	8.6 ± 4.6	2.9 ± 3.7*
LARS score, mean ± SD	−14.5 ± 9.1	−25.0 ± 5.5*
MATTIS score, mean ± SD	127 ± 14
NPI, median ± SD	1.6 ± 2.1
Semantic fluency score, mean ± SD	14.4 ± 4.8
Phonemic fluency score, mean ± SD	9.1 ± 4.8
Clock Drawing Test score, mean ± SD	8.9 ± 2.2

PD: Parkinson’s disease; SD: standard deviation; UPDRS: Unified Parkinson Disease Rating Scale; NPI: neuropsychiatric inventory; LARS: Lille apathy rating scale; MEC: Mini-Mental State Examination; MADRS: Montgomery and Åsberg depression rating scale; MATTIS: Mattis Dementia Rating Scale. *Significant differences between both groups, < 0,001.