Table 2: Main characteristics of RCTs for ARDS patients included in this study.

AuthorYearPatientsLow PEEP levelHigh PEEP level

Amato et al. [38]1998ARDS≥5 cm H2O16 cm H2O or Pflex + 2
Ranieri et al. [39]1999ARDS3–15 cm H2O15 cm H2O or Pflex + 3
The NHLBI Institute ARDS Clinical Trial Network [40]2004ALI/ARDS5 cm H2O5–24 cm H2O according FiO2
Villar et al. [50]2006ARDS≥5 cm H2O15 cm H2O or Pflex + 3
Mercat et al. [41]2008ALI/ARDS5–9 cm H2OPEEP according to Plateau 28–30 cm H2O
Meade et al. [42]2008ALI/ARDS5 cm H2O5–24 according FiO2
Talmor et al. [43]2008ALI/ARDS10 cm H2O17 cm H2O