Research Article

Clinical Factors Associated with Sperm DNA Fragmentation in Male Patients with Infertility

Table 4

The correlations between the sperm DNA fragmentation index and the clinical parameters.

Variableρ values

Age (years old)0.09448 0.49678
Duration of infertility (months)0.15084 0.27626
Serum LH (mIU/mL)0.09629 0.48855
Serum FSH (mIU/mL)0.27100 0.04747*
Serum total testosterone (ng/mL)0.07281 0.60082
Serum free testosterone (pg/mL)0.05565 0.69519
Brinkman index#0.10040 0.47442
Body mass index (kg/m2)0.17027 0.21835
Conventional semen analysis
 Abstinence (days)−0.122760.37651
 Semen volume (mL)−0.10769 0.43829
 Normal sperm morphology (%)−0.43883 0.00090*
 Sperm count ( /mL)−0.25931 0.05829
 Total sperm count ( )−0.30078 0.02710
 Sperm progressive motility (%)−0.55996 0.00001*
 Motile sperm count ( /mL)−0.49420 0.00015*
 Total motile sperm count ( )−0.48962 0.00017*
Computer-assisted semen analysis
 Linear velocity (μm/sec)−0.01841 0.89488
 Curvilinear velocity (μm/sec)−0.26853 0.04960*
 Linearity0.31185 0.02170*
 Amplitude of lateral head
 displacement (μm)
−0.33075 0.01457*
 Beat/cross frequency (Hz)−0.14489 0.29587
High-magnification microscopy
 Proportion of vacuolated sperm (%)0.25746 0.06538

LH: luteinizing hormone; ρ: Spearman’s rank correlation coefficient; FSH: follicle-stimulating hormone; statistically significant; daily number of cigarettes × years.