4-Hydroxy-2-nonenal Induces Apoptosis by Inhibiting AKT Signaling in Human Osteosarcoma Cells
Figure 3
4-HNE activates apoptotic signaling in MG63 cells. (a)-(b) Western blots (a) and histograms (b) showing the decreasing of protein levels of BcL-2 by 4-HNE treatment (5 to 50 μM, and 2 h to 4 h) in MG63 cells. Results are averages of three independent experiments. (c)-(d) Western blots (c) and histograms (d) showing the increasing of protein levels of Bax by 4-HNE treatment (5 to 50 μM, and 2 h to 4 h) in MG63 cells. Results are averages of three independent experiments.
