Research Article
Overexpression of MMP13 Is Associated with Clinical Outcomes and Poor Prognosis in Oral Squamous Cell Carcinoma
Figure 4
Immunohistochemistry of MMP13. Normal oral mucosa (a) H&E stain (magnification 400x and 1600x); (e) anti-MMP13 antibody immunostain was negative in the normal oral mucosa (magnification 400x and 1600x). Dysplastic oral tissue (b) H&E stain (magnification 800x and 1600x); (f) anti-MMP13 antibody showed weak to moderate immunostaining in the cytoplasm of the dysplastic epithelial cells (magnification 800x and 1600x). OSCC (c and d) H&E stained (magnification 800x and 1600x); (g) anti-MMP13 antibody immunostaining showed low expression and (h) high expression in the cytoplasm of the epithelial tumor cells (magnification 800x and 1600x). All the oral tissues showed moderate anti-MMP13 antibody immunostaining of the stroma and inflammatory cells in the microenvironment.