Clinical Study

Investigation of the Effects of Curcumin on Serum Cytokines in Obese Individuals: A Randomized Controlled Trial

Table 1

Effect of curcumin on serum cytokine concentrations.

Study group PeriodPeriod effectCarryover effectTreatment effect
12
BaselineEndpointBaselineEndpoint

IL-1α (pg/mL)Curcumin-placebo15 0.230.270.58
Placebo-curcumin15
IL-1β (pg/mL)Curcumin-placebo15 0.310.130.042
Placebo-curcumin15
IL-2 (pg/mL)Curcumin-placebo15 0.520.840.22
Placebo-curcumin15
IL-4 (pg/mL)Curcumin-placebo15 0.860.010.008
Placebo-curcumin15
IL-6 (pg/mL)Curcumin-placebo15 0.320.650.76
Placebo-curcumin15
IL-8 (pg/mL)Curcumin-placebo15 0.080.400.69
Placebo-curcumin15
IL-10 (pg/mL)Curcumin-placebo15 0.510.100.82
Placebo-curcumin15
IFNγ (pg/mL)Curcumin-placebo15 0.920.470.63
Placebo-curcumin15
EGF (pg/mL)Curcumin-placebo15 0.140.420.73
Placebo-curcumin15
VEGF (pg/mL)Curcumin-placebo15 0.010.400.03
Placebo-curcumin15
MCP-1 (pg/mL)Curcumin-placebo15 0.090.350.54
Placebo-curcumin15
TNFα (pg/mL)Curcumin-placebo15 0.640.330.42
Placebo-curcumin15 0

Values are expressed as mean ± SD. IL: interleukin; EGF: epidermal growth factor; VEGF: vascular endothelial growth factor; MCP-1: macrophage chemoattractant protein 1; TNF : tumor necrosis factor .