Release Behavior and Toxicity Profiles towards Leukemia (WEHI-3B) Cell Lines of 6-Mercaptopurine-PEG-Coated Magnetite Nanoparticles Delivery System

Table 2

Correlation coefficient, rate constant, and half-time obtained by fitting the data of the release of MP from FPEGMP-2 nanocomposite into phosphate-buffered solution at pH 4.8 and 7.4.

Aqueous solution	Saturated release %	𝑅^2			Rate constant (𝑘)^a(mg/min)	𝑡1/2^a (min)
		Pseudo-first order	Pseudo-second order	Parabolic diffusion
pH 7.4	59.6	0.4017	0.9990	0.4876	1.89×10^−4	93
pH 4.8	97.2	0.9168	0.9950	0.9567	5.59×10^−4	22

aEstimated using pseudo-second order kinetics.