Research Article

Gossypol Promotes Degeneration of Ovarian Follicles in Rats

Table 2

Serum concentrations of estradiol, progesterone, luteinizing hormone (LH), thyroxine (T4), triiodothyronine (T3), and thyroid stimulating hormone (TSH) in female rats dosed with gossypol (25 mg/kg/day) or 0.9% saline (control group) subcutaneously for 15 consecutive days.

Control ( )Gossypol ( ) value1

T4 (ng/dL) 0.01446
T3 (pg/mL) n.s.
T3/T4 ratio 0.02635
TSH ( IU/mL) n.s.
Progesterone (ng/mL) 0.01317
LH (mIU/mL) n.s.
Estradiol (pg/mL) n.s.

Welch’s test.
n.s.: not significant ( ).