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The Scientific World Journal
Volume 2015, Article ID 303415, 7 pages
http://dx.doi.org/10.1155/2015/303415
Research Article

Evaluation of Cinnamomum osmophloeum Kanehira Extracts on Tyrosinase Suppressor, Wound Repair Promoter, and Antioxidant

1Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan
2Division of Urology, Department of Surgery, Zuoying Branch of Kaohsiung Armed Forces General Hospital, Kaohsiung 813, Taiwan
3Department of Fragrance and Cosmetic Science, Graduate Institute of Natural Products, Center for Stem Cell Research, Kaohsiung Medical University, No. 100, Shih-Chuan 1st Road, San-Ming District, Kaohsiung 80708, Taiwan
4Department of Bioscience Technology, Chang Jung Christian University, Tainan 711, Taiwan
5Metal Industries Research & Development Centre, Kaohsiung 812, Taiwan
6State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau
7Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong
8Marine Biomedical Laboratory & Center for Translational Biopharmaceuticals, Department of Marine Biotechnology and Resources, National Sun Yat-sen University, 70 Lien-Hai Road, Kaohsiung 804, Taiwan

Received 28 May 2014; Revised 30 July 2014; Accepted 2 August 2014

Academic Editor: Li-Yeh Chuang

Copyright © 2015 Man-Gang Lee et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Cinnamomum osmophloeum Kanehira belongs to the Lauraceae family of Taiwan’s endemic plants. In this study, C. osmophloeum Kanehira extract has shown inhibition of tyrosinase activity on B16-F10 cellular system first. Whether extracts inhibited mushroom tyrosinase activity was tested, and a considerable inhibition of mushroom tyrosinase activity by in vitro assays was presented. Animal experiments of C. osmophloeum Kanehira were carried out by observing animal wound repair, and the extracts had greater wound healing power than the vehicle control group (petroleum jelly with 8% DMSO, w/v). In addition, the antioxidant capacity of C. osmophloeum Kanehira extracts in vitro was evaluated. We measured C. osmophloeum Kanehira extract’s free radical scavenging capability, metal chelating, and reduction power, such as biochemical activity analysis. The results showed that a high concentration of C. osmophloeum Kanehira extract had a significant scavenging capability of free radical, a minor effect of chelating ability, and moderate reducing power. Further exploration of the possible physiological mechanisms and the ingredient components of skincare product for skin-whitening, wound repair, or antioxidative agents are to be done.