Effects of 5-Amyno-4-(1,3-benzothyazol-2-yn)-1-(3-methoxyphenyl)-1,2-dihydro-3H-pyrrol-3-one Intake on Digestive System in a Rat Model of Colon Cancer

Figure 2

Microphotographs of rat colon ((a), (e), (i), (m), and (q)), gastric ((b), (f), (j), (n), and (r)) and jejunal ((c), (g), (k), (o), and (s)) mucosa, and liver periportal zone ((d), (h), (l), (p), and (t)); hematoxylin-eosin-orange stain; magnification 400x. Experimental groups: control: (a), (b), (c), and (d); DMH: (e), (f), (g), and (h); DMH + : (i), (j), (k), and (l); DMH + : (m), (n), (o), and (p); DMH + 5FU: (q), (r), (s), and (t). Inflammatory features in groups DMH ((e), (g), and (h)), DMH + (l), DMH + ((m), (n), and (o)), and DMH + 5FU ((q) and (s)) are manifested by lymphatic and histiocytic cells infiltration, marked by red arrows, and blood capillary dilations, marked by yellow arrows. Damage of surface epithelium appeared in groups DMH ((f) and (g)) and DMH + 5FU ((q), (r), and (s)) and appeared less in DMH + (o).

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