Research Article
Effects of 5-Amyno-4-(1,3-benzothyazol-2-yn)-1-(3-methoxyphenyl)-1,2-dihydro-3H-pyrrol-3-one Intake on Digestive System in a Rat Model of Colon Cancer
Table 1
Tumor parameters for rats treated by D1 and 5FU under DMH-induced carcinogenesis. Mean ± SEM,
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| | DMH | DMH + | DMH + | DMH + 5FU |
| Total tumors | Tumor number | 9.56 ± 1.74 | 5.60 ± 1.27 () | 7.17 ± 1.70 | 4.78 ± 1.44 () | Tumor total area, cm2 | 1.58 ± 0.65 | 0.94 ± 0.40 () | 0.86 ± 0.47 () | 0.91 ± 0.68 () |
| Exophytic tumors | Tumor number | 9.00 ± 1.53 | 4.90 ± 1.38 () | 6.50 ± 2.23 | 4.44 ± 1.42 () | Tumor total area, cm2 | 1.03 ± 0.28 | 0.49 ± 0.16 () | 0.56 ± 0.37 () | 0.46 ± 0.21 () |
| Endophytic tumors | Tumor number | 0.67 ± 0.47 | 0.70 ± 0.60 | 0.67 ± 0.67 | 0.33 ± 0.31 | Tumor total area, cm2 | 0.55 ± 0.53 | 0.45 ± 0.42 | 0.3 ± 0.27 | 0.45 ± 0.42 |
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values indicated in comparison with DMH group.
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