Research Article

Effects of 5-Amyno-4-(1,3-benzothyazol-2-yn)-1-(3-methoxyphenyl)-1,2-dihydro-3H-pyrrol-3-one Intake on Digestive System in a Rat Model of Colon Cancer

Table 1

Tumor parameters for rats treated by D1 and 5FU under DMH-induced carcinogenesis. Mean ± SEM, .

DMHDMH +  DMH +  DMH + 5FU

Total tumors
Tumor number9.56 ± 1.745.60 ± 1.27 ()7.17 ± 1.704.78 ± 1.44 ()
Tumor total area, cm21.58 ± 0.650.94 ± 0.40 ()0.86 ± 0.47 ()0.91 ± 0.68 ()

Exophytic tumors
Tumor number9.00 ± 1.534.90 ± 1.38 ()6.50 ± 2.234.44 ± 1.42 ()
Tumor total area, cm21.03 ± 0.280.49 ± 0.16 ()0.56 ± 0.37 ()0.46 ± 0.21 ()

Endophytic tumors
Tumor number0.67 ± 0.470.70 ± 0.600.67 ± 0.670.33 ± 0.31
Tumor total area, cm20.55 ± 0.530.45 ± 0.420.3 ± 0.270.45 ± 0.42

values indicated in comparison with DMH group.