Research Article

Effects of 5-Amyno-4-(1,3-benzothyazol-2-yn)-1-(3-methoxyphenyl)-1,2-dihydro-3H-pyrrol-3-one Intake on Digestive System in a Rat Model of Colon Cancer

Table 3

Morphometric parameters of gastric mucosa for rats treated by D1 and 5FU under DMH-induced carcinogenesis. Mean ± SEM, .

Mucosa thickness, mChief cells cross-sectional area, m2Chief cells nuclei cross-sectional area, m2Parietal cells cross-sectional area, m2Parietal cells nuclei cross-sectional area, m2

Control512.77 ± 3.846.97 ± 1.410.03 ± 0.28121.43 ± 2.3217.03 ± 0.46

572.38 ± 2.34 ()50.25 ± 1.36 ()10.02 ± 0.27 ()138.05 ± 2.32 ()18.12 ± 0.34 ()

583.01 ± 1.84 ()54.96 ± 0.74 ()11.41 ± 0.3 ()142.40 ± 3.61 ()19.23 ± 0.36 ()

5FU424.13 ± 3.72 ()39.11 ± 0.73 ()8.45 ± 0.44 ()106.71 ± 1.53 ()14.13 ± 0.35 ()

DMH408.38 ± 1.82 ()32.70 ± 0.88 ()7.26 ± 0.45 ()98.33 ± 2.95 ()10.34 ± 0.29 ()

DMH + 458.81 ± 2.42 (, , )41.64 ± 0.56 (, )9.42 ± 0.12 (, , )114.23 ± 2.8 (, )12.30 ± 0.15 (, , )

DMH + 444.05 ± 3.24 (, )37.16 ± 0.4 (, , )8.82 ± 0.18 (, , )104.72 ± 2.39 (, , )11.10 ± 0.15 (, , )

DMH + 5FU443.82 ± 2.39 (, )40.21 ± 0.67 (, )8.16 ± 0.16 (, )111.32 ± 3.27 (, )14.2 ± 0.61 (, )

values indicated in comparison with control; compared to DMH group; compared to DMH + 5FU group: for DMH + and DMH + groups.