Research Article
Formulation and Evaluation of Galantamine Gel as Drug Reservoir in Transdermal Patch Delivery System
Table 2
Percentage of drug release at 8 h from different gel formulations (mean ± S.D.;
).
| | Factors | Weight percentage (% w/w) | Drug release percentage at 8 h (%) |
| | Carbopol amount | 0.50 | | | 1.00 | 32.47 ± 0.23 | | 2.00 | 17.79 ± 0.08 | | 5.00 | 12.48 ± 0.05 |
| | Triethanolamine amount | 1.00 | 66.42 ± 0.51 | | 3.00 | | | 5.00 | 1.37 ± 0.00 |
| | Galantamine hydrobromide amount | 1.00 | 14.71 ± 0.04 | | 3.00 | | | 5.00 | 97.94 ± 0.50 |
| | Propylene glycol amount | 0.00 | 1.35 ± 0.00 | | 1.00 | 1.37 ± 0.01 | | 5.00 | 26.33 ± 0.24 | | 10.00 | |
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denotes the repeated formulations, with the same composition.
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