Lack of Association between rs2067474 Polymorphism in Histamine Receptor H₂ Gene and Breast Cancer in Chinese Han Population

Table 1

Characteristics of breast cancer patients and control participants.

	Breast cancer ()	Control ()
Age (years)	46.5 ± 9.2	47.2 ± 7.9	0.381^a
BMI (kg/m^2)	23.1 ± 2.9	22.6 ± 2.7	0.049^a
Sex
Women	201 (100%)	238 (100%)	—
Menopausal state
Premenopausal	126 (62.7%)	131 (55.0%)	0.120^b
Postmenopausal	75 (37.3%)	107 (45.0%)
Tumor size (cm)
2.0	44 (21.9%)
>2.0	157 (78.1%)
Histology
DIC	176 (87.6%)
LIC	9 (4.4%)
Others	16 (8.0%)
Clinical stages
I or II	158 (78.6%)
III or IV	43 (21.4%)
Lymph node metastasis
Node-negative	116 (58.0%)
Node-positive	85 (42.0%)
Hormone receptor status
Negative	56 (27.9%)
Positive	145 (72.1%)
HER2 status
0-1	98 (48.8%)
2-3	103 (51.2%)

BMI: body mass index, DIC: ductal invasive carcinoma, and LIC: lobular invasive carcinoma.
^aP values were calculated by Student’s -tests.
^bP values were calculated from two-sided chi-square test.