Ultrastructural Changes in Clinical and Microbiota Isolates of Klebsiella pneumoniae Carriers of Genes bla_SHV, bla_TEM, bla_CTX-M, or bla_KPC When Subject to β-Lactam Antibiotics

Figure 4

(a–i) Scanning electron micrographs of isolate K652. (a-b) Control cells with preserved morphology. (c-d) Cells subjected to CTX (98 μg mL⁻¹). Observe spherical cells that are not grown being formed from cells with preserved morphology. (e–g) Cells subjected to CAZ (27 μg mL⁻¹). Observe elongated cells forming bacterial filaments. (h-i) Cells subjected to IMP (16 μg mL⁻¹). Observe elongated cells due to unfinished successive divisions. Bars = 2 μm. CAZ: ceftazidime; CTX: cefotaxime; and IMP: imipenem.

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