Review Article

Association between Polymorphism of Interleukin-1beta and Interleukin-1 Receptor Antagonist Gene and Asthma Risk: A Meta-Analysis

Table 1

Main data of all studies included in the meta-analysis for the -511C/T polymorphism in IL-1β gene.

Reference, yearEthnicitySource of controlMean of age (years)Cases/controlCasesControl
(country)TTTCCCTTTCCC

Hang et al. 2003 [35]Asian (Taiwan)HB27.4116/4740542218227
Hsieh et al. 2004 [40]Asian (Taiwan)HB10202/144699340487026
Karjalainen et al. 2003 [38]Caucasian (Finland)PB5899/98374517424115
Lim et al. 2011 [28]Asian (Singapore)HB63.5299/7168315561200359157
Mahdaviani et al. 2009 [30]Caucasian (Iran)HB17.940/1406522368221
Karjalainen et al. 2002 [39]Caucasian (Finland)PB57.7200/2008482346910229
Rezaei et al. 2009 [29]Caucasian (Iran)PB8.630/28082117216642
Wu et al. 2007 [41]Asian (China)HB39.576/76243616263812
Zeyrek et al. 2008 [31]Caucasian (Turkey)PB9.4268/22854168466613626
Zhao et al. 2006 [42]Asian (China)HB5.955/3545105300

HB: hospital-based case-control; PB: population-based case-control.