Fibrin Gel as an Injectable Biodegradable Scaffold and Cell Carrier for Tissue Engineering

Figure 5

Masson’s trichrome staining of infarction site after eight weeks for treatment with bone marrow mononuclear cells delivered with ((a), (b), and (c)) and without ((d), (e), and (f)) fibrin gel. The infarction size of treatment with fibrin gel (arrows) is smaller than the treatment without fibrin gel. Treatment with cell-fibrin gel mixture demonstrated a larger amount of viable tissue (red) and a smaller amount of fibrous tissue (blue) when compared to the direct injection of cells without fibrin gel. Scale bar indicates 2 mm in (a), (b), (d), and (e) and 100 μm in (c) and (f) [47].