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The Scientific World Journal
Volume 2015 (2015), Article ID 712683, 6 pages
Clinical Study

Herbal Mouthwash Containing Extracts of Baccharis dracunculifolia as Agent for the Control of Biofilm: Clinical Evaluation in Humans

1Department of Dental Materials and Prosthodontics, Ribeirão Preto Dentistry Faculty, University of São Paulo, 14040-904 Ribeirão Preto, SP, Brazil
2Multidisciplinary Institute for Health, Federal University of Bahia, Anísio Teixeira Campus, 45029-094 Vitoria da Conquista, BA, Brazil
3Department of Morphology, Physiology and Basic Pathology, Ribeirão Preto Dentistry Faculty, University of São Paulo, 14040-904 Ribeirão Preto, SP, Brazil

Received 13 August 2014; Revised 14 October 2014; Accepted 27 October 2014

Academic Editor: Toni Zeinoun

Copyright © 2015 Vinícius Pedrazzi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Baccharis dracunculifolia DC (Asteraceae), popularly known as “alecrim-do-campo,” is largely distributed in South America, is shown to exhibit protective actions against gastric ulcers, has anti-inflammatory properties, and is hepatoprotective. Several essential oils obtained from Baccharis species possess biological activities, such as antimicrobial and antivirus activities. This randomized controlled trial evaluated the efficacy of B. dracunculifolia in the reduction of dental biofilm, comparing this natural product with other mouthwashes already known in the dental market. In measuring the time after use of mouthwash (), there was no difference between products (); that is, subjects in the study had a similar PI after the first use. After one week (), there was no difference between the four products evaluated (), so, all research individuals completed the study with a similar reduction in dental biofilm between themselves but it was different from initial state (Friedman test). It is possible to conclude that B. dracunculifolia had the same efficiency of the materials used to oral hygiene in reduction of dental plaque and, consequently, prevention of dental caries. Thus, we can consider B. dracunculifolia as a good candidate for new material to be implemented in dental care.