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The Scientific World Journal
Volume 2015, Article ID 751703, 8 pages
http://dx.doi.org/10.1155/2015/751703
Clinical Study

Methotrexate Associated Renal Impairment Is Related to Delayed Elimination of High-Dose Methotrexate

Division of Hematology-Oncology, Children’s Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China

Received 29 April 2015; Accepted 8 June 2015

Academic Editor: Xu Dong Zhang

Copyright © 2015 Shi-Long Yang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [5 citations]

The following is the list of published articles that have cited the current article.

  • Shachar Raz, Michal Stark, and Yehuda G. Assaraf, “Folylpoly-γ-glutamate synthetase: A key determinant of folate homeostasis and antifolate resistance in cancer,” Drug Resistance Updates, 2016. View at Publisher · View at Google Scholar
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  • Shu-Mei Wang, Wei-Xin Zeng, Wan-Shui Wu, Lu-Lu Sun, and Dan Yan, “ Association between MTHFR microRNA binding site polymorphisms and methotrexate concentrations in Chinese pediatric patients with acute lymphoblastic leukemia ,” The Journal of Gene Medicine, pp. e2990, 2017. View at Publisher · View at Google Scholar
  • Kalthi Vaishnavi, Deepak Bansal, Amita Trehan, Richa Jain, and Savita Verma Attri, “Improving the safety of high-dose methotrexate for children with hematologic cancers in settings without access to MTX levels using extended hydration and additional leucovorin,” Pediatric Blood & Cancer, pp. e27241, 2018. View at Publisher · View at Google Scholar
  • Dao-Hai Cheng, Hua Lu, Tao-Tao Liu, Xiao-Qin Zou, and Hui-Mei Pang, “Identification of Risk Factors in High-Dose Methotrexate-Induced Acute Kidney Injury in Childhood Acute Lymphoblastic Leukemia,” Chemotherapy, vol. 63, no. 2, pp. 100–106, 2018. View at Publisher · View at Google Scholar