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The Scientific World Journal
Volume 2015, Article ID 956235, 7 pages
http://dx.doi.org/10.1155/2015/956235
Research Article

Royal Jelly and Its Dual Role in TNBS Colitis in Mice

1Department of Pharmacology, Faculty of Medical Sciences, University of Campinas (UNICAMP), 13083-970 Campinas, SP, Brazil
2Department of Structural and Functional Biology, Institute of Biology, University of Campinas (UNICAMP), 13083-970 Campinas, SP, Brazil
3Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas (UNICAMP), 13083-970 Campinas, SP, Brazil
4Department of Biological Sciences, Federal University of Goiás (UFG), Regional Catalão, 75704-020 Catalão, GO, Brazil

Received 28 July 2014; Revised 15 October 2014; Accepted 22 October 2014

Academic Editor: Inaya Hajj Hussein

Copyright © 2015 Luis Paulo Manzo et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. M. F. Ramadan and A. Al-Ghamdi, “Bioactive compounds and health-promoting properties of royal jelly: a review,” Journal of Functional Foods, vol. 4, no. 1, pp. 39–52, 2012. View at Publisher · View at Google Scholar · View at Scopus
  2. P. Moutsatsou, Z. Papoutsi, E. Kassi et al., “Fatty acids derived from royal jelly are modulators of estrogen receptor functions,” PLoS ONE, vol. 5, no. 12, Article ID e15594, 2010. View at Publisher · View at Google Scholar · View at Scopus
  3. T. Sugiyama, K. Takahashi, and H. Mori, “Royal jelly acid, 10-Hydroxy-trans-2-decenoic acid, as a modulator of the innate immune responses,” Endocrine, Metabolic & Immune Disorders—Drug Targets, vol. 12, no. 4, pp. 368–376, 2012. View at Publisher · View at Google Scholar · View at Scopus
  4. K. Kohno, I. Okamoto, O. Sano et al., “Royal jelly inhibits the production of proinflammatory cytokines by activated macrophages,” Bioscience, Biotechnology and Biochemistry, vol. 68, no. 1, pp. 138–145, 2004. View at Publisher · View at Google Scholar · View at Scopus
  5. S. Watanabe, K. Suemaru, K. Takechi, H. Kaji, K. Imai, and H. Araki, “Oral mucosal adhesive films containing royal jelly accelerate recovery from 5-fluorouracil-induced oral mucositis,” Journal of Pharmacological Sciences, vol. 121, no. 2, pp. 110–118, 2013. View at Publisher · View at Google Scholar · View at Scopus
  6. K. Niu, H. Guo, Y. Guo et al., “Royal jelly prevents the progression of sarcopenia in aged mice in vivo and in vitro,” The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, vol. 68, no. 12, pp. 1482–1492, 2013. View at Publisher · View at Google Scholar · View at Scopus
  7. F. C. Thien, R. Leung, B. A. Baldo, J. A. Weiner, R. Plomley, and D. Czarny, “Asthma and anaphylaxis induced by royal jelly,” Clinical and Experimental Allergy, vol. 26, no. 2, pp. 216–222, 1996. View at Publisher · View at Google Scholar · View at Scopus
  8. M. Takahashi, I. Matsuo, and M. Ohkido, “Contact dermatitis due to honeybee royal jelly,” Contact Dermatitis, vol. 9, no. 6, pp. 452–455, 1983. View at Publisher · View at Google Scholar · View at Scopus
  9. Y. Yonei, K. Shibagaki, N. Tsukada et al., “Case report: haemorrhagic colitis associated with royal jelly intake,” Journal of Gastroenterology and Hepatology, vol. 12, no. 7, pp. 495–499, 1997. View at Publisher · View at Google Scholar · View at Scopus
  10. J.-R. Liu, Y.-C. Yang, L.-S. Shi, and C.-C. Peng, “Antioxidant properties of royal jelly associated with larval age and time of harvest,” Journal of Agricultural and Food Chemistry, vol. 56, no. 23, pp. 11447–11452, 2008. View at Publisher · View at Google Scholar · View at Scopus
  11. S. J. Dixon and B. R. Stockwell, “The role of iron and reactive oxygen species in cell death,” Nature Chemical Biology, vol. 10, no. 1, pp. 9–17, 2014. View at Publisher · View at Google Scholar · View at Scopus
  12. V. Chiurchiù and M. MacCarrone, “Chronic inflammatory disorders and their redox control: from molecular mechanisms to therapeutic opportunities,” Antioxidants and Redox Signaling, vol. 15, no. 9, pp. 2605–2641, 2011. View at Publisher · View at Google Scholar · View at Scopus
  13. F. M. de Faria, A. Luiz-Ferreira, E. A. R. Socca et al., “Effects of Rhizophora mangle on experimental colitis induced by TNBS in rats,” Evidence-Based Complementary and Alternative Medicine, vol. 2012, Article ID 753971, 11 pages, 2012. View at Publisher · View at Google Scholar · View at Scopus
  14. D. Owczarek, D. Cibor, M. Szczepanek, and T. Mach, “Biological therapy of inflammatory bowel disease,” Polskie Archiwum Medycyny Wewnetrznej, vol. 119, no. 1-2, pp. 84–88, 2009. View at Google Scholar · View at Scopus
  15. J. Y. Cho, S.-G. Chi, and H. S. Chun, “Oral administration of docosahexaenoic acid attenuates colitis induced by dextran sulfate sodium in mice,” Molecular Nutrition & Food Research, vol. 55, no. 2, pp. 239–246, 2011. View at Publisher · View at Google Scholar · View at Scopus
  16. L. Márquez, B. G. Pérez-Nievas, I. Gárate et al., “Anti-inflammatory effects of Mangifera indica L. extract in a model of colitis,” World Journal of Gastroenterology, vol. 16, no. 39, pp. 4922–4931, 2010. View at Publisher · View at Google Scholar · View at Scopus
  17. T. Karaca, F. Bayiroglu, M. Yoruk et al., “Effect of royal jelly on experimental colitis induced by acetic acid and alteration of mast cell distribution in the colon of rats,” European Journal of Histochemistry, vol. 54, no. 4, article e35, 2010. View at Google Scholar · View at Scopus
  18. G. P. Morris, P. L. Beck, M. S. Herridge, W. T. Depew, M. R. Szewczuk, and J. L. Wallace, “Hapten-induced model of chronic inflammation and ulceration in the rat colon,” Gastroenterology, vol. 96, no. 3, pp. 795–803, 1989. View at Google Scholar · View at Scopus
  19. J. L. Wallace, W. K. MacNaughton, G. P. Morris, and P. L. Beck, “Inhibition of leukotriene synthesis markedly accelerates healing in a rat model of inflammatory bowel disease,” Gastroenterology, vol. 96, no. 1, pp. 29–36, 1989. View at Google Scholar · View at Scopus
  20. M. E. Anderson, “Determination of glutathione and glutathione disulfide in biological samples,” Methods in Enzymology, vol. 113, pp. 548–555, 1985. View at Publisher · View at Google Scholar · View at Scopus
  21. T. Yoshikawa, Y. Naito, A. Kishi et al., “Role of active oxygen, lipid peroxidation, and antioxidants in the pathogenesis of gastric mucosal injury induced by indomethacin in rats,” Gut, vol. 34, no. 6, pp. 732–737, 1993. View at Publisher · View at Google Scholar · View at Scopus
  22. M. Helenius, M. Hänninen, S. K. Lehtinen, and A. Salminen, “Changes associated with aging and replicative senescence in the regulation of transcription factor nuclear factor-κB,” Biochemical Journal, vol. 318, part 2, pp. 603–608, 1996. View at Google Scholar · View at Scopus
  23. M. M. Bradford, “A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding,” Analytical Biochemistry, vol. 72, no. 1-2, pp. 248–254, 1976. View at Publisher · View at Google Scholar · View at Scopus
  24. U. K. Laemmli, “Cleavage of structural proteins during the assembly of the head of bacteriophage T4,” Nature, vol. 227, no. 5259, pp. 680–685, 1970. View at Publisher · View at Google Scholar · View at Scopus
  25. Y. Liu, Z. Zhang, L. Wang et al., “TLR4 monoclonal antibody blockade suppresses dextran-sulfate-sodium-induced colitis in mice,” Journal of Gastroenterology and Hepatology, vol. 25, no. 1, pp. 209–214, 2010. View at Publisher · View at Google Scholar · View at Scopus
  26. A. A. te Velde, M. I. Verstege, and D. W. Hommes, “Critical appraisal of the current practice in murine TNBS-induced colitis,” Inflammatory Bowel Diseases, vol. 12, no. 10, pp. 995–999, 2006. View at Publisher · View at Google Scholar · View at Scopus
  27. A. M. Gómez-Caravaca, M. Gómez-Romero, D. Arráez-Román, A. Segura-Carretero, and A. Fernández-Gutiérrez, “Advances in the analysis of phenolic compounds in products derived from bees,” Journal of Pharmaceutical and Biomedical Analysis, vol. 41, no. 4, pp. 1220–1234, 2006. View at Publisher · View at Google Scholar · View at Scopus
  28. J. Bouayed and T. Bohn, “Exogenous antioxidants—double-edged swords in cellular redox state: health beneficial effects at physiologic doses versus deleterious effects at high doses,” Oxidative Medicine and Cellular Longevity, vol. 3, no. 4, pp. 228–237, 2010. View at Publisher · View at Google Scholar · View at Scopus
  29. N. Kannan and C. Guruvayoorappan, “Protective effect of Bauhinia tomentosa on acetic acid induced ulcerative colitis by regulating antioxidant and inflammatory mediators,” International Immunopharmacology, vol. 16, no. 1, pp. 57–66, 2013. View at Publisher · View at Google Scholar · View at Scopus
  30. E. A. Rabelo Socca, A. Luiz-Ferreira, F. M. De Faria et al., “Inhibition of tumor necrosis factor-alpha and cyclooxigenase-2 by Isatin: a molecular mechanism of protection against TNBS-induced colitis in rats,” Chemico-Biological Interactions, vol. 209, no. 1, pp. 48–55, 2014. View at Publisher · View at Google Scholar · View at Scopus
  31. A. Siomek, “NF-κB signaling pathway and free radical impact,” Acta Biochimica Polonica, vol. 59, no. 3, pp. 323–331, 2012. View at Google Scholar · View at Scopus
  32. G. Rogler, K. Brand, D. Vogl et al., “Nuclear factor κB is activated in macrophages and epithelial cells of inflamed intestinal mucosa,” Gastroenterology, vol. 115, no. 2, pp. 357–369, 1998. View at Publisher · View at Google Scholar · View at Scopus
  33. M. E. Spehlmann and L. Eckmann, “Nuclear factor-kappa B in intestinal protection and destruction,” Current Opinion in Gastroenterology, vol. 25, no. 2, pp. 92–99, 2009. View at Publisher · View at Google Scholar · View at Scopus
  34. I. Dey, M. Lejeune, and K. Chadee, “Prostaglandin E 2 receptor distribution and function in the gastrointestinal tract,” The British Journal of Pharmacology, vol. 149, no. 6, pp. 611–623, 2006. View at Publisher · View at Google Scholar · View at Scopus
  35. D. G. Binion, M. F. Otterson, and P. Rafiee, “Curcumin inhibits VEGF-mediated angiogenesis in human intestinal microvascular endothelial cells through COX-2 and MAPK inhibition,” Gut, vol. 57, no. 11, pp. 1509–1517, 2008. View at Publisher · View at Google Scholar · View at Scopus
  36. H. Behzad, A. Sharma, R. Mousavizadeh, A. Lu, and A. Scott, “Mast cells exert pro-inflammatory effects of relevance to the pathophyisology of tendinopathy,” Arthritis Research and Therapy, vol. 15, no. 6, article R184, 2013. View at Publisher · View at Google Scholar · View at Scopus