Research Article
Origanum majorana Essential Oil Lacks Mutagenic Activity in the Salmonella/Microsome and Micronucleus Assays
Table 5
Replication index of cultures exposed to Origanum majorana essential oil for 3 h or 21 h.
| | Substance | Concentration | 3 h | 21 h | | Replication factor (mean ± S.D.) | Replication index (%) | Replication factor (mean ± S.D.) | Replication index (%) |
| | — | | 100 | | 100 | | Essential oil | 0.003125 μL/mL | | 101 | | 100 | | 0.00625 μL/mL | | 96 | | 99 | | 0.0125 μL/mL | | 101 | | 102 | | 0.025 μL/mL | | 99 | | 94 | | 0.75 μg/mL | | 69 | — | — | | 0.25 μg/mL | — | — | | 94 |
|
|
control: DMSO (0.5%). control.
|
