The Scientific World Journal

Research Article

In Vitro Antifungal Activity of Hexahydropyrimidine Derivatives against the Causative Agents of Dermatomycosis

Table 1

Antifungal activity of hexahydropyrimidine derivatives and reference drugs.
Compound T. mentagrophytes ATCC 9538M. canis ATCC 32903M. gypseum ATCC 14683T. rubrum CCT 5507
URM 1666
MIC
MFC		1,000
1,000		>1,000
>1,000		>1,000
>1,000		500
500
MIC
MFC		>1,000
>1,000		>1,000
>1,000		>1,000
>1,000		>1,000
>1,000
MIC
MFC		500
1,000		500
1,000		500
1,000		250
500
MIC
MFC		1,000
>1,000		1,000
>1,000		1,000
>1,000		250
1,000
MIC
MFC		1
4		8
16		10
160		16
16
MIC
MFC		3
3		0.1875
0.1875		0.1171
0.1171		0.1875
0.1875
MIC = minimal inhibitory concentration; MFC = minimal fungicidal concentration. The results were expressed in µg mL−1.