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Figure 3: Histological changes with DNBS-induced colitis in mice after 14 days. (a) Mice having instillation of 50% ethanol were used as the control. (b) Mice had rectal instillation of DNBS only. (c–e) Mice had rectal instillation of DNBS and then were injected with different concentration of LSA (50 μg/mL, 100 μg/mL, and 200 μg/mL), respectively. (f) Histological colitis scores of individual mice are shown as circles, and the averages of each group are shown as horizontal bars. Each symbol represents an individual animal. Representative pictures of each group are shown. Groups B and C had significantly higher colitis scores than Group E ((a) p > 0.05 and (b) p < 0.01, respectively). L: gut lumen; M: muscle; U: ulcer; arrow: inflammatory infiltrate. Magnification 200×.