Review Article

The Epidemiology of Hepatitis D Virus in North Africa: A Systematic Review and Meta-Analysis

Table 1

Prevalence of antihepatitis D virus and hepatitis D virus RNA in HBsAg-positive populations in North Africa.

YearCategoryTested (n)Anti-HDVHDV RNA
n (%)95% CIn (%)95% CI

Egypt
2000Out-patients454 (9)2.91-14.891(25)19-34
2010Liver disease patients142 (14)8.94-19.66--
2010Liver disease patients304 (13)8.52-18.081(25)17-32
2013Blood donors1708 (5)1.58-7.82--
2016Hospital patients12110 (8)2.16-14.443(30)7-74

Libya
2015General population3462(2)1.0-2.0--
2012Hospital patients1624 (3)1.0-4.111(25)5-68

Tunisia
2013General population46421(4.5)1.56-7.44
2013 Liver disease patients226(27.2)9.87-44.532(33)31-79
2013Liver disease patients5510(18.1)7.91-28.293(30)29-71
2015General population1615216(2)1.21- 2.79--
Sudan
2015Hospital patients904(4.4)1.75-7.05--
2015Hemodialysis patients906(7.36)3.86-10.86--
2015Pregnant women903(3.3)1.41-5.191(30)32-69

Mauretania
2008Blood donors44778(19)15-2454(69)52-78
2009Pregnant women10914(13)8-2711(79)42-91
2009Hospital patients16229(18)14-2821(72)51-86

Algeria
2013General population29612(4.0)2.0-6.0--

Morocco
2010General population56119 (3.0)1.0-6.0--