Research Article

Comparison of Predictive In Silico Tools on Missense Variants in GJB2, GJB6, and GJB3 Genes Associated with Autosomal Recessive Deafness 1A (DFNB1A)

Figure 2

The correlation coefficient (r) histogram. Note. r: the relationship between the known clinical significance of missense variants and in silico evaluation given by 9 predictive tools; α: the level of significance of the correlation coefficient: the critical value for the significance level and the sample size n=9 is 0.933, so the correlation is significant at p<0.001 [23].