Twenty Element Concentrations in Human Organs Determined by Two-Jet Plasma Atomic Emission Spectrometry

Table 2

The content of different elements in lyophilized preparations of human organs (μg/g).

Element	Average value ± SD or concentration range as well as literature data taken from [46] are in parentheses
	Organ
	Lung (n = 6)	Spleen (n = 6)	Liver (n = 6)	Kidney (n = 6)	Muscle (n = 5)	Heart (n = 6)	Brain (n = 1)
Ag	<0.02–0.06	<0.02	<0.02–0.2	<0.02–0.11	<0.03–0.05	<0.02–0.05	<0.03
Al	263 ± 163 (130 ± 203)	14.5 ± 15.5 (12.5 ± 4.3)	5.9 ± 4.8 (11.3 ± 3.2)	7.4 ± 4.3 (10.4 ± 3.4)	2.2 ± 1.8 (9.4 ± 2.3)	9.2 ± 4.2 (11.4 ± 5.3)	2.1 (13.9 ± 3.2)
B	2.5 ± 1.2	<0.5–1.0	0.8 ± 0.26	0.95 ± 0.50	0.6 ± 0.2	0.57 ± 0.13	0.59
Ba^β	6.9 ± 8.1^ῼ	<0.3	<0.2–2.8	<0.2–0.40	<0.3–0.3	0.36 ± 0.22	<0.3
Ca	1650 ± 565 (585 ± 205)	511.7 ± 103.0 (335 ± 149)	323 ± 78 (208 ± 121)	1232 ± 410 (529 ± 291)	442 ± 439 (215 ± 90)	413 ± 251 (291 ± 151)	430 (301 ± 187)
Cd	<0.1–7.0 (<4–11.7)	1.3 ± 1.2 (5.4 ± 6.7)	11.5 ± 9.1 (16.7 ± 19.1)	114 ± 122^ῼ (237 ± 206)	0.95 ± 1.0^ῼ (<0.3–4.8)	<0.1–0.51 (<0.4–7)	0.24 (0.4)
Co	<0.2–0.92 (<0.005–1.4)	<0.3 (<0.001–0.09)	<0.2–1.0 (0.17 ± 0.11)	<0.2–0.38 (0.07 ± 0.1)	<0.2 (<0.001–0.03)	<0.2–0.74 (0.07 ± 0.048)	<0.2 (<0.001–0.07)
Cr	4.0 ± 1.3	<0.5	<0.5	<0.5	<0.5	<0.5	<0.5
Cu	15.2 ± 3.8 (<2.0–38)	10.6 ± 4.8 (<1.5–11)	19.8 ± 5.7 (32 ± 20)	17.5 ± 4.5 (<2.3–45)	4.2 ± 1.4 (<0.8–39)	16.5 ± 6.3 (18.0 ± 5.5)	47 (24 ± 11)
Fe	2900 ± 498 (984 ± 489)	2650 ± 1595 (1400 ± 760)	723 ± 489 (837 ± 522)	825 ± 299 (430 ± 203)	156 ± 18 (136 ± 42)	428 ± 222 (257 ± 80)	440 (225 ± 71)
Mg	1093 ± 161 (<11–1390)	1305 ± 391 (729 ± 216)	603 ± 220 (678 ± 191)	1160 ± 271 (<13–1250)	968 ± 225 (911 ± 153)	1185 ± 517 (1070 ± 210)	1260 (700 ± 244)
Mn	2.7 ± 0.8 (1.17 ± 0.94)	1.3 ± 1.0 (0.82 ± 0.71)	8.5 ± 2.0 (5.58 ± 1.78)	7.9 ± 1.5 (4.92 ± 1.64)	0.47 ± 0.21 (0.74 ± 1.44)	0.86 ± 0.30 (1.63 ± 2.16)	1.8 (1.32 ± 0.49)
Mo	0.33 ± 0.06 (<0.01–2.7)	<0.3–3.7 (<0.37–1.4)	4.9 ± 1.0 (2.1 ± 1.8)	1.9 ± 0.60 (<0.47–2.1)	<0.2 (<0.31–2.2)	<0.2–0.55 (<0.14–3.9)	<0.2 (<0.02–1.65)
Ni	3.1 ± 2.0	<0.5	<0.3	0.82 ± 0.85^ῼ	<0.5	<0.5	<0.5
Pb	<0.3–0.4	<0.5–0.66	<0.5–0.65	<0.5–1.7	<0.5–0.64	<0.5	1.9
Si	2390 ± 1829	164 ± 107	40.8 ± 29.3	78.2 ± 18.6	31.6 ± 8.3	66.5 ± 40.4	39
Sn	3.2 ± 2.1	<0.5	<0.3–1.1	<0.5	<0.5	<0.5	<0.3
Sr	1.0 ± 0.66	0.40 ± 0.17	0.56 ± 0.52	0.6 ± 0.3	0.42 ± 0.31	0.2 ± 0.09	0.34
Ti	31 ± 17	<2–18	<2	≤2–3.7	<2	<2–2.9	<2
Zn	208 ± 35 (62 ± 19)	156 ± 135 (83 ± 21)	272 ± 153 (228 ± 85)	292 ± 156 (235 ± 70)	290 ± 103 (237 ± 55)	218 ± 92 (126 ± 28)	120 (51 ± 15)

Literature data from [46] obtained by neutron activation analysis are given in parentheses. Element concentrations in 7 different organs were determined by two-jet plasma atomic emission spectrometry; the relative standard deviation of the results from three replicates in the case of each sample analyzed was within 3–12%. The obtained average values for 5-6 samples in the case of seven organs are used to calculate average value ± SD. The data of two-jet plasma atomic emission spectrometry contained reliable peaks corresponding to some elements, but it was possible to estimate only their approximate concentration. ^ῼIn the absence of the Gaussian distribution for several samples, the SD was higher than the average value; in this case, the median (M) and interquartile ranges (IQR) were estimated (see Supplementary Tables 1–6). ^βIn one of the donors, the content of Ba in various organs was approximately 3–3000 times higher than in other ones. Therefore, the content of Ba in organs of this donor was not taken into account to calculate the average value and is separately given in Table 3.