Effect of Long-Term Moderate Physical Exercise on Irisin between Normal Weight and Obese Men

Table 1

Differences of metabolic variables and irisin in normal weight and obese groups in each four assessments and during six months of physical exercises.

Variables	Months	Normal weight	Obese	value
BMI (kg/m^2)
	0	23.00 ± 0.62	42.98 ± 1.80	0.0001
	2	22.86 ± 0.68	42.56 ± 1.60	0.0001
	4	22.77 ± 0.70	41.38 ± 1.43	0.0001
	6	22.65 ± 0.88	35.85 ± 1.66	0.0001
value		NS	NS
WC (cm)
	0	76.31 ± 0.80	104.16 ± 3.98	0.0001
	2	76.11 ± 0.78	103.89 ± 3.30	0.0001
	4	75.97 ± 0.75	103.34 ± 1.75	0.0001
	6	75.94 ± 0.78	100.11 ± 3.09	0.0001
value		NS	NS
FBS (mmol)
	0	4.71 ± 0.10	6.98 ± 0.19	0.0001
	2	4.54 ± 0.11	6.65 ± 0.14	0.0001
	4	4.42 ± 0.08	6.63 ± 0.16	0.0001
	6	4.17 ± 0.08	6.11 ± 0.08	0.0001
value		0.005	NS
Insulin (ng/ml)
	0	7.83 ± 0.87	24.48 ± 2.72	0.0001
	2	6.15 ± 1.49	22.07 ± 1.78	0.0001
	4	5.84 ± 0.91	20.51 ± 1.96	0.0001
	6	5.04 ± 0.69	16.14 ± 2.81	0.0001
value		NS	0.05
HOMA-IR
	0	1.60 ± 0.20	7.57 ± 1.18	0.0001
	2	1.51 ± 0.20	6.65 ± 1.11	0.0001
	4	1.36 ± 0.16	5.29 ± 0.69	0.0001
	6	1.26 ± 0.14	4.13 ± 0.51	0.0001
value		0.05	0.005
HOMA-B2
	0	129.98 ± 17.47	140.92 ± 17.59	0.0001
	2	119.44 ± 33.28	140.31 ± 13.35	0.0001
	4	127.54 ± 21.78	131.48 ± 15.33	0.0001
	6	152.19 ± 30.66	123.27 ± 20.59	0.0001
value		NS	0.05
Irisin (ng/ml)
	0	87.54 ± 6.08	91.10 ± 4.71	0.05
	2	90.56 ± 4.79	107.01 ± 6.40	0.0001
	4	93.46 ± 5.17	124.32 ± 6.68	0.0001
	6	97.39 ± 5.68	139.50 ± 6.96	0.0001
value		0.01	0.0001

BMI: body mass index, WC: waist circumference, FBS: fasting blood sugar; HOMA-IR: homeostatic model assessment of insulin resistance index, HOMA-B2: homeostatic model assessment of insulin of pancreatic cells-beta, NS: nonsignificant.