Macrophylloflavone: A New Biflavonoid from Garcinia macrophylla Mart. (Clusiaceae) for Antibacterial, Antioxidant, and Anti-Type 2 Diabetes Mellitus Activities
Table 3
The effect of compound 1 on blood glucose levels of diabetic rats.
No.
Treatment
Blood glucose levels (mean ± SD, mg/dL)
Pretreatment blood
Diabetic blood
Posttreatment blood
1
B0
105.00 ± 3.94
396.00 ± 3.67
412.20 ± 7.76
B1
88.20 ± 4.17
339.20 ± 12.49
98.00 ± 1.67
B2
103.40 ± 6.80
377.00 ± 25.33
171.00 ± 3.81
B3
87.00 ± 4.42
357.40 ± 28.87
138.00 ± 1.87
B4
93.80 ± 11.12
379.40 ± 21.33
108.40 ± 3.21
2
ANOVA table
F (DFn, DFd)
value
Interaction
F (8, 40) = 146.2
<0.0001
Dose (biflavonoid and control)
F (2, 40) = 2985
<0.0001
Blood glucose level
F (4, 20) = 239
<0.0001
3
Tukey’s post hoc test
value
Significant?
B0 versus B1
<0.0001
Yes
B1 versus B2
<0.0001
Yes
B1 versus B3
0.0049
Yes
B1 versus B4
0.0055
Yes
Different letters indicate significant differences between the groups (). Tukey’s post hoc test following the two-way ANOVA. B0: the negative control, B1: the positive control, B2: the compound 1 given at a dose of 6 μg/kg body weight, B3: the compound 1 given at a dose of 7 μg/kg body weight, B4: the compound 1 given at a dose of 8 μg/kg body weight.
