Research Article

Antibacterial Activity of Defatted and Nondefatted Methanolic Extracts of Aframomum melegueta K. Schum. against Multidrug-Resistant Bacteria of Clinical Importance

Table 1

Bacterial susceptibility to different standard antibiotic disks.

Average inhibition zones (±1.00) produced by different standard antibiotics

Organisms usedOFLCPRGENCFRCFZAMPNITAUG
(5 µg)(5 µg)(10 µg)(30 µg)(30 µg)(10 µg)(300 µg)(30 µg)
(mm)

Micrococcus luteus15 ± 1.0016 ± 1.0016 ± 1.006 ± 1.006 ± 1.006 ± 1.0015 ± 1.006 ± 1.00
Bacillus subtilis KZN26 ± 1.0024 ± 1.0025 ± 1.006 ± 1.006 ± 1.006 ± 1.0027 ± 1.006 ± 1.00
Escherichia coli ATCC 2592220 ± 1.0020 ± 1.0010 ± 1.006 ± 1.006 ± 1.006 ± 1.006 ± 1.006 ± 1.00
Staphylococcus aureus NCTC 657128 ± 1.0025 ± 1.0014 ± 1.0021 ± 1.006 ± 1.006 ± 1.006 ± 1.006 ± 1.00
Klebsiella pneumoniae ATCC 435225 ± 1.0025 ± 1.0015 ± 1.006 ± 1.006 ± 1.006 ± 1.0013 ± 1.006 ± 1.00
Aeromonas hydrophila ATCC 3565415 ± 1.0025 ± 1.0015 ± 1.006 ± 1.006 ± 1.006 ± 1.0015 ± 1.006 ± 1.00
Klebsiella pneumoniae ATCC 1003125 ± 1.0025 ± 1.0013 ± 1.006 ± 1.006 ± 1.006 ± 1.006 ± 1.006 ± 1.00
Plesiomonas shigelloides ATCC 5190315 ± 1.0016 ± 1.006 ± 1.006 ± 1.006 ± 1.006 ± 1.006 ± 1.006 ± 1.00
Pseudomonas aeruginosa ATCC 1544215 ± 1.0014 ± 1.006 ± 1.006 ± 1.006 ± 1.006 ± 1.006 ± 1.006 ± 1.00
Pseudomonas aeruginosa ATCC 1958230 ± 1.0025 ± 1.0015 ± 1.006 ± 1.006 ± 1.006 ± 1.0015 ± 1.006 ± 1.00

Ofl = ofloxacin; Cpr = ciprofloxacin; Gen = gentamicin; Cfr = cefuroxime; Cfz = ceftazidime; Amp = ampicillin; Aug = augumentin; Nit = nitrofurantoin.