Antibacterial Activity of Defatted and Nondefatted Methanolic Extracts of Aframomum melegueta K. Schum. against Multidrug-Resistant Bacteria of Clinical Importance

Table 2

Antibacterial activity of the different extracts of Aframomum melegueta using agar well diffusion assay.

	Average inhibition zones (±1.0 mm) produced by the different extracts of A. melegueta
	NHE			NDME			DME
Organisms used	10	1	0.1	10	1	0.1	10	1	0.1
	(mg/mL)
Micrococcus luteus	6 ± 1.00	6 ± 1.00	6 ± 1.00	19 ± 1.00	6 ± 1.00	6 ± 1.00	25 ± 1.00	18 ± 1.00	6 ± 1.00
Bacillus subtilis KZN	6 ± 1.00	6 ± 1.00	6 ± 1.00	29 ± 1.00	6 ± 1.00	6 ± 1.00	40 ± 1.00	15 ± 1.00	6 ± 1.00
Escherichia coli ATCC 25922	6 ± 1.00	6 ± 1.00	6 ± 1.00	14 ± 1.00	6 ± 1.00	6 ± 1.00	29 ± 1.00	14 ± 1.00	6 ± 1.00
Staphylococcus aureus NCTC 6571	6 ± 1.00	6 ± 1.00	6 ± 1.00	19 ± 1.00	6 ± 1.00	6 ± 1.00	23 ± 1.00	6 ± 1.00	6 ± 1.00
Klebsiella pneumoniae ATCC 4352	6 ± 1.00	6 ± 1.00	6 ± 1.00	14 ± 1.00	6 ± 1.00	6 ± 1.00	20 ± 1.00	6 ± 1.00	6 ± 1.00
Aeromonas hydrophila ATCC 35654	6 ± 1.00	6 ± 1.00	6 ± 1.00	20 ± 1.00	6 ± 1.00	6 ± 1.00	25 ± 1.00	16 ± 1.00	12 ± 1.00
Klebsiella pneumoniae ATCC 10031	6 ± 1.00	6 ± 1.00	6 ± 1.00	14 ± 1.00	6 ± 1.00	6 ± 1.00	20 ± 1.00	6 ± 1.00	6 ± 1.00
Plesiomonas shigelloides ATCC 51903	6 ± 1.00	6 ± 1.00	6 ± 1.00	11 ± 1.00	6 ± 1.00	6 ± 1.00	24 ± 1.00	6 ± 1.00	6 ± 1.00
Pseudomonas aeruginosa ATCC 15442	6 ± 1.00	6 ± 1.00	6 ± 1.00	20 ± 1.00	6 ± 1.00	6 ± 1.00	30 ± 1.00	20 ± 1.00	14 ± 1.00
Pseudomonas aeruginosa ATCC 19582	6 ± 1.00	6 ± 1.00	6 ± 1.00	16 ± 1.00	6 ± 1.00	6 ± 1.00	30 ± 1.00	15 ± 1.00	6 ± 1.00

NHE = n-hexane extract; NDME = nondefatted methanol extract; DME = defatted methanol extract.