Herbal Medicinal Products from Passiflora for Anxiety: An Unexploited Potential

Table 1

List of clinical trials related to the use of Passiflora to treat anxiety registered in NIH.

Trial number	Dosage form	Formulation NAME	Stage	Period	Reference anxiolytic AGENT	Status
NCT00794456	Tablet	Pasalix: Passiflora incarnata L., Crataegus oxyacantha L., Salix alba L.	Phase 3	6 weeks	Valeriana officinalis L. (50 mg)	Completed Oct 2013
NCT01178632	Tablet	Passiflorine: Passiflora incarnata L., Crataegus oxyacantha L., Salix alba L.	Phase 3	4 weeks	Valeriana officinalis L.	Unknown
NCT00944268	Liquid	Passiflora incarnata L., Crataegus oxyacantha L., Salix alba L.	Phase 3	30 days	None	Unknown
NCT02065843	Capsules	Passiflora incarnata L. 100 mg	Phase 2 phase 3	1 h before dental surgery	Midazolam (15 mg)	Completed Sep 2014
NCT03909906	tablets	Euphytose®: 50 mg Valeriana officinalis L., 40 mg Passiflora incarnata L., 10 mg Crataegus sp., 10 mg Ballota nigra L.	Not applicable	14 days	None	Completed Dec 2019
NCT00997490	Film-coated sugar-pill	Neurapas balance: hypericum, valerian, passionflower	Phase 3	6 weeks	None	Completed Feb 2003

Source: https://www.clinicaltrials.gov/. Accessed on May 19, 2020.