Environmentally Friendly Methods for Flavonoid Extraction from Plant Material: Impact of Their Operating Conditions on Yield and Antioxidant Properties

Table 1

Representation of the most common extraction conditions and equipment used in the different conventional methods.

Equipment	Most used solvents/temperature and time range	Reference
	Water; Ethanol (EtOH); Methanol (MeOH); EtOH-Water mixture (50–90%); MeOH-water mixture (60–70%); 60–95°C; 15 min–12 h	[51, 55–58]
	EtOH; MeOH; EtOH-water mixture (30–90%); MeOH- water mixture (60–90%); 20–60°C; 2–72 h	[53, 57, 59–65]
	Water; EtOH; MeOH; EtOH-water mixture (50–95%); MeOH-water mixture (80%); 10–25°C; 24–72 h	[66–70]
	Water; 100°C; 5–30 min; Used for hard plant material such as roots, barks, stems, and seeds	[71–75]
	Water; 100°C; 5–30 min; Used for soft plant material such as flowers and leaves	[74–77]
	Water; EtOH; MeOH; EtOH-water mixture (50–96%); MeOH-water mixture (60–96.6%); Petroleum ether; Acetonitrile; Acetone; Ethyl acetate; Dichloromethane; Hexane; Boiling point of solvent; 2–48 h	[59, 62, 64, 69, 73, 78–83]