Regenerative Endodontic Therapy in the Management of Immature Necrotic Permanent Dentition: A Systematic Review

Table 4

Summary of all old systematic reviews in the scope of our systematic review.

Authors	Year	Number of studies used	Method summary	Main conclusions
Bucchi et al. [66]	2017	23 studies	The systematic review summaries and presents different clinical and animal studies performed. Only those articles published up to May 2016 were considered for review. Using 7 different databases (MEDLINE, Scopus, Cochrane library, SciELO, Google Scholar, Science Direct, and EMBASE), an electronic search was performed.	Most of the included studies did not follow a standard clinical protocol for regenerative endodontic therapy.
Antunes et al. [67]	2016	11 studies	A systematic review summarizes and presents original articles in the database Web of Science, PubMed, BVS (Medline, SciELO, Lilacs, and BBO), Scopus, and Cochrane. Only those articles published up to July 2014 were considered for review, and analysis of the papers published during this period took place based on previously established criteria, through the methodology of a systematic review.	Significant outcomes have appeared in the pulp revascularization, but several aspects remain unknown, such as the key factors of this repair, the type of tissue formed, and the long-term prognosis.