Evaluation of Antidiabetic Properties of the Leaves Extract of Ficus vallis-choudae Delile in a Model of Type 2 Diabetes Induced by High-Fat Diet and Streptozotocin

Table 3

Effect of AEFV on the lipids profile and cardiovascular indices.

Parameters	Normal control	Diabetic control	Metformin		AEFV
			(40 mg/kg)	110 mg/kg	220 mg/kg	440 mg/kg
HDL-c (mg/dL)	47.16 ± 4.00	11.99 ± 0.54	42.61 ± 0.23^c	39.88 ± 0.54^c	40,29 ± 0.39^c	41.75 ± 0.59^c
LDL-c (mg/dL)	37.04 ± 0.52	94.47 ± 0.98	48.72 ± 0.98^c	56.57 ± 2.98^c	54,37 ± 2.84^c	52.26 ± 0.44^c
TG (mg/dL)	91.07 ± 3.97	158.53 ± 7.13	96.17 ± 0.49^c	98.75 ± 7.14^c	97,09 ± 6.78^c	95.10 ± 4.52^c
TC (mg/dL)	112.61 ± 2.63	202.20 ± 0.80	135.54 ± 4.68^c	123.81 ± 2.80^c	134,36 ± 2.16^c	126.13 ± 5.67^c
VLDL-c (mg/dL)	18.21 ± 0.79	31.70 ± 1.42	18.73 ± 0.57^c	19.75 ± 1.42^c	19,41 ± 1.35^c	19.02 ± 0.90^c
AI	1.44 ± 0.22	15.96 ± 0.80	2.18 ± 0.12^c	2.10 ± 0.07^c	2,34 ± 0.03^c	2.01 ± 0.09^c
CI	1.27 ± 0.10	0.12 ± 0.007	0.87 ± 0.02^c	0.71 ± 0.04^c	0,74 ± 0.05^c	0.79 ± 0.01^c
CRI	1.98 ± 0.21	13.35 ± 1.10	2.19 ± 0.07^c	2.47 ± 0.17^c	2,41 ± 0.16^c	2.28 ± 0.12^c

All results were expressed as mean ± standard derivation (n = 5). Data analysis was performed by one-way ANOVA followed by Turkey’s post hoc test. statistically significant compared with the normal control group. statistically significant compared with the diabetic control. AEFV: aqueous extract of the leaves of Ficus vallis-choudae; CI: cardioprotective index; TC: total cholesterol; TG: triglycerides; HDL-c: high-density lipoprotein cholesterol; LDL-c: low-density lipoprotein cholesterol; VLDL-c: very-low-density lipoprotein cholesterol; AI: atherogenic index; CRI: coronary artery risk index.