Bioactivity and Biotechnological Overview of Naturally Occurring Compounds from the Dinoflagellate Family Symbiodiniaceae: A Systematic Review

Table 2

Symbiodiniaceae-derived metabolites with the reported bioactivity and microalgae strain source.

Compound no.	Metabolite	Bioactivity	Symbiodiniaceae strain	References
1	Zooxanthellatoxin A	Vasoconstriction, platelet aggregation	S9	[47, 55, 56]
2	Zooxanthellatoxin B	Vasoconstriction	S9	[46, 47]
3	Zooxanthellamide A	N/A^b	S2	[39]
4	Zooxanthellamide B	N/A	S2	[40]
5	Zooxanthellamide C	Vasoconstriction	S2	[41]
6	Zooxanthellamide D	Cytotoxicity	S3	[42]
7	Symbiodinolide	N-type Ca^2+ channel inhibition, COX-2 inhibition (anti-inflammatory)	S12	[53]
8	Symbioramide-C16	N/A	S9	[48]
9	Zooxanthellactone	Cytotoxicity	S4	[43]
10	Symbiospirol A	Protein kinase C inhibition (anti-inflammatory)	S12	[54]
11	Symbiospirol B	N/A	S12	[54]
12	Symbiospirol C	N/A	S12	[54]
13	Symbiodinolactone A	N/A	S1	[38]
14	Pseudopterosin A	N/A	S10	[15, 49, 50]
15	Pseudopterosin B	N/A	S10	[15, 49, 50]
16	Pseudopterosin C	N/A	S10	[15, 49, 50]
17	Pseudopterosin D	N/A	S10	[15, 49, 50]
18	Fuscol	N/A	S11	[50]
19	Symbioimine	Osteoclastogenesis inhibition, COX-2 inhibition (anti-inflammatory)	S12	[51, 52]
20	Neosymbioimine	N/A	S12	[52]
21	Zooxanthellabetaine A	N/A	S9	[48]
22	Zooxanthellamine	N/A	S9	[48]
23	Peridinin	Delayed-type hypersensitivity inhibition (anti-inflammatory)	S5	[44]

^aAssigned compound number. ^bN/A: not available.