The Scientific World Journal

Research Article

An Efflux Pumps Inhibitor Significantly Improved the Antibacterial Activity of Botanicals from Plectranthus glandulosus towards MDR Phenotypes

Table 1

Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) in μg/mL of crude extracts and fractions from P. glandulosus and chloramphenicol against selected Gram-negative bacteria.
BacteriaTested samples, MICs (MBCs) in μg/mL
ExtractFraction BFraction CFraction DFraction EFraction FFraction GFraction HChloramphenicol
Escherichia coli         
 ATCC 8739-512 (>512)32 (>512)64 (>512)>512>512>512>5122 (64)
 AG 102-512 (>512)256 (>512)256 (>512)512 (>512)>512)>512>51232 (256)
Enterobacter aerogenes         
 ATCC 13048-512 (>512)128 (>512)512 (>512)512 (>512)>512>512>51232 (128)
 EA 27->512256 (>512)512 (>512)>512512 (512)>512>51216 (256)
Klebsiella pneumoniae         
 ATCC 11296-512 (>512)256 (>512)512 (>512)512 (>512)>512>512>5128 (256)
 KP 55->51264 (>512)512 (>512)512 (>512)>512>512>51232 (256)
Providencia stuartii         
 ATCC 29916->512>512512 (>512)512 (>512)512 (>512)>512>51264 (256)
 PS 2636-256 (>512)256 (>512)512 (>512)512 (>512)>512>512>51264 (256)
Pseudomonas aeruginosa         
 PA 01-256 (>512)>512>512512 (>512)>512>512>51264 (>256)
 PA 124-256 (>512)256 (>512)512 (>512)512 (>512)>512>512>51264 (>256)
(-): ≥1024 μg/mL; MIC, minimum inhibitory concentration; MBC, minimum bactericidal concentration.