Predicting the Most Deleterious Missense Nonsynonymous Single-Nucleotide Polymorphisms of Hennekam Syndrome-Causing CCBE1 Gene, In Silico Analysis

Table 6

TM‐score and RMSD values of 23 selected damaging nsSNPs in CCBE1.

SNP-ID	Residual change	TM-score	RMSD values	SNP-ID	Residual change	TM-score	RMSD values
rs199902030	D336N	0.92174	1.25	rs121908252	G327R	0.91250	1.36
rs200149541	T153N	0.95561	0.84	rs121908254	C174R	0.92822	1.46
rs372499913	G107D	0.95388	1.13	rs147974432	T144M	0.93348	1.13
rs267605221	P249S	0.91250	1.36	rs192224843	Q353R	0.92957	1.32
rs374941368	S19N	0.92526	1.44	rs115982879	R118L	0.92844	1.57
rs375717418	R301W	0.93696	1.02	rs139059968	K355T	0.93921	1.01
rs80008675	D41E	0.95466	1.12	rs141125426	D397Y	0.96008	1.06
rs149792489	A96G	0.92689	1.50	rs147208835	R125W	0.96213	0.89
rs116675104	R167W	0.93715	1.16	rs147681552	P290L	0.92174	1.25
rs121908250	C75S	0.96248	0.90	rs148498685	P87S	0.93523	1.14
rs121908251	C102S	0.96432	1.22	rs149531418	G330E	0.94082	1.12