Comparative Study of Antiproliferative Activity in Different Plant Parts of Phaleria macrocarpa and the Underlying Mechanism of Action

Table 1

IC₅₀ of various parts of P. macrocarpa.

Sample	IC50 value (μg/mL ± SD)		Selectivity index (SI)	SI activity
	T47D	TIG
Pericarp	125 ± 2.33	594 ± 2.77	4.7	High selectivity
Mesocarp	144 ± 1.18	472 ± 2.67	3.3	High selectivity
Seed	139 ± 1.14	538 ± 2.73	3.9	High selectivity
Leaves	97 ± 1.82	414 ± 2.62	4.3	High selectivity

Data are expressed as mean ± SD. SI (selectivity index) = IC50 on normal cell line/IC50 on cancer cell line. SI value >3 indicated a high selective extract. Data are presented as mean ± SD of three independent experiments.