The Scientific World Journal

Flavonoids: Separation and Quantitation


Publishing date
12 Sep 2014
Status
Published
Submission deadline
04 Jul 2014

1Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand

2Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Corvallis, OR, USA

3School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan


Flavonoids: Separation and Quantitation

Description

Flavonoids are widely distributed in plants as secondary products with many metabolic functions. This group of polyphenols represents one of the most abundant classes of phytochemicals that are ubiquitously present in fruits, vegetables, medicinal plants, and their products. Thousands of flavonoids, existing both as free forms and as glycosides, have been characterized. Many of them are known to be related to a wide array of ecological interactions of plants, and some of the flavonoids have been found to act as signal and defense molecules. At present, however, there is still a concern that many minor flavonoids present in plant tissues have not yet been identified.

In addition, flavonoids are renowned for their health benefits with scientific evidence supporting that regular intake of dietary flavonoids reduces the risk of oxidative-stress mediated pathogenesis of human diseases as well as of age-related ailments. In many cases, however, it is the form of flavonoid-containing extracts that possess interesting biological and pharmacological activities. For further development of heath products or drugs, the extracts are needed to be separated to obtain the flavonoid constituents, either for the analytical (as chromatograms) or preparative (as single compounds) purposes.

With the high interest in the flavonoids as bioactive compounds involved in both aspects of ecological interactions and health promotions, more and more new and minor natural flavonoids have been isolated and identified with interesting biological activities. At the same time, several techniques of chromatography have been further developed for efficient separation, identification, and quantitation of the flavonoids. Therefore, in this special issue, we invite investigators to contribute original research articles and review articles that will stimulate the continuing efforts to develop superior methods with significant novelty of flavonoid separation and quantitative analysis. In addition, other nonflavonoid polyphenols can also be considered for this special issue. Potential topics include, but are not limited to:

  • Advances in HPLC-, GC-, and HPTLC-based techniques for effective separation and quantitation of bioactive flavonoids
  • Method development for quick identification of bioactive flavonoid(s) from chemical profiles or patterns (e.g., directly on a HPTLC plate or from HPLC eluates)

Before submission authors should carefully read over the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/tswj/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/tswj/analytical.chemistry/flav/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2015
  • - Article ID 874148
  • - Editorial

Flavonoids: Separation and Quantitation

Wanchai De-Eknamkul | Kaoru Umehara | Jan Frederik Stevens
  • Special Issue
  • - Volume 2015
  • - Article ID 947248
  • - Research Article

Antimycobacterial and Nitric Oxide Production Inhibitory Activities of Ocotea notata from Brazilian Restinga

Isabela Francisca Borges Costa | Sanderson Dias Calixto | ... | Michelle Frazão Muzitano
  • Special Issue
  • - Volume 2014
  • - Article ID 506971
  • - Research Article

Microwave-Assisted Simultaneous Extraction of Luteolin and Apigenin from Tree Peony Pod and Evaluation of Its Antioxidant Activity

Hongzheng Wang | Lei Yang | ... | Xiuhua Zhao
  • Special Issue
  • - Volume 2014
  • - Article ID 724267
  • - Research Article

Analysis of Flavone C-Glycosides in the Leaves of Clinacanthus nutans (Burm. f.) Lindau by HPTLC and HPLC-UV/DAD

June Lee Chelyn | Maizatul Hasyima Omar | ... | Zakiah Ismail
  • Special Issue
  • - Volume 2014
  • - Article ID 306217
  • - Research Article

Phenolic Composition and Antioxidant Activity of Malus domestica Leaves

Mindaugas Liaudanskas | Pranas Viškelis | ... | Valdimaras Janulis
  • Special Issue
  • - Volume 2014
  • - Article ID 283024
  • - Research Article

Optimization of Ionic Liquid Based Simultaneous Ultrasonic- and Microwave-Assisted Extraction of Rutin and Quercetin from Leaves of Velvetleaf (Abutilon theophrasti) by Response Surface Methodology

Chunjian Zhao | Zhicheng Lu | ... | Yuangang Zu
  • Special Issue
  • - Volume 2014
  • - Article ID 181072
  • - Research Article

Phytochemical Profiles and Antioxidant and Antimicrobial Activities of the Leaves of Zanthoxylum bungeanum

Yujuan Zhang | Ziwen Luo | ... | Dengwu Li
  • Special Issue
  • - Volume 2014
  • - Article ID 523120
  • - Research Article

Optimization of Reflux Conditions for Total Flavonoid and Total Phenolic Extraction and Enhanced Antioxidant Capacity in Pandan (Pandanus amaryllifolius Roxb.) Using Response Surface Methodology

Ali Ghasemzadeh | Hawa Z. E. Jaafar
  • Special Issue
  • - Volume 2014
  • - Article ID 528653
  • - Research Article

HPLC-Fingerprints and Antioxidant Constituents of Phyla nodiflora

Fang-Ju Lin | Feng-Lin Yen | ... | Horng-Huey Ko
  • Special Issue
  • - Volume 2014
  • - Article ID 303878
  • - Research Article

Flavonoids in Juglans regia L. Leaves and Evaluation of In Vitro Antioxidant Activity via Intracellular and Chemical Methods

Ming-Hui Zhao | Zi-Tao Jiang | ... | Rong Li
The Scientific World Journal
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Acceptance rate24%
Submission to final decision97 days
Acceptance to publication42 days
CiteScore1.430
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