Table of Contents
Volume 2011, Article ID 142719, 9 pages
Research Article

Cytoprotective Effect of Morinda tinctoria Roxb. against Surgical and Chemical Factor Induced Gastric and Duodenal Ulcers in Rats

Department of Pharmacology and Toxicology, C.L. Baid Metha College of Pharmacy, Jyothi Nagar, Thoraipakkam, Chennai 600 097, India

Received 17 October 2011; Revised 9 November 2011; Accepted 14 November 2011

Academic Editor: T. Arakawa

Copyright © 2011 D. Sivaraman and P. Muralidharan. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. H. M. T. El-Zimaity, “Recent advances in the histopathology of gastritis,” Current Diagnostic Pathology, vol. 13, no. 4, pp. 340–348, 2007. View at Publisher · View at Google Scholar · View at Scopus
  2. S. Dhikav, S. Sing, and S. Pande, “Non-steroidal drug-induced gastrointestinal toxicity: mechanisms and management,” Journal, Indian Academy of Clinical Medicine, vol. 4, no. 4, 2003. View at Google Scholar
  3. WHO Expert Committee on Diabetes Mellitus, Technical Reports Series, World Health Organisation, Geneva, Switzerland, 1980.
  4. W. Whistler, Tongan Herbal Medicine, Isle Botanica, Honolulu, Hawaii, USA, 1992.
  5. M. Y. Wang, B. J. West, C. J. Jensen et al., “Morinda citrifolia (Noni): a literature review and recent advances in Noni research,” Acta Pharmacologica Sinica, vol. 23, no. 12, pp. 1127–1141, 2002. View at Google Scholar · View at Scopus
  6. O. Levand and H. O. Larson, “Some chemical constituents of Morinda citrifolia,” Planta Medica, vol. 36, no. 2, pp. 186–187, 1979. View at Google Scholar · View at Scopus
  7. J. P. Farine, L. Legal, B. Moreteau, and J. L. Le Quere, “Volatile components of ripe fruits of Morinda citrifolia and their effects on Drosophila,” Phytochemistry, vol. 41, no. 2, pp. 433–438, 1996. View at Google Scholar · View at Scopus
  8. N. K. Moorthy and G. S. Reddy, “Preliminary phytochemical and pharmacological study of Morinda tinctoria,” Linn. Antiseptic, vol. 67, pp. 167–171, 1970. View at Google Scholar
  9. J. Singh and R. D. Tiwari, “Flavone glycosides from the flowers of Morinda citrofolia,” Journal of the Indian Chemical Society, vol. 53, no. 4, article 424, 1976. View at Google Scholar · View at Scopus
  10. J. B. Harbone, Phyto Chemical Methods, Chapman & Hall, London, UK, 1973.
  11. G. E. Trease and W. C. Evans, “Pharmacognosy,” in Phenols and Phenolic Glycosides, pp. 223–249, ELBS, London, UK, 1989. View at Google Scholar
  12. J. Donald Ecobichon, The Basis of Toxicity Testing, CRC Press, New York, NY, USA, 1997.
  13. J. Jayaraman, Laboratory Manual in Biochemistry, New Age International, New Delhi, India, 1st edition, 1981.
  14. H. Gerhard Vogel, Drug Discovery and Evaluation—Pharmacological Assays, Springer, Heidelberg, Germany, 2002.
  15. E. J. Beckers, N. J. Rehrer, F. Brouns, F. Ten Hoor, and W. H. M. Saris, “Determination of total gastric volume, gastric secretion and residual meal using the double sampling technique of George,” Gut, vol. 29, no. 12, pp. 1725–1729, 1988. View at Google Scholar · View at Scopus
  16. A. Hussain and S. S. Habib, “Effect of cimetidine on reduction of gastric secretion and ph in adult patients undergoing elective surgery and its impact on aspiration risk,” Pakistan Journal of Physiology, vol. 3, no. 1, pp. 8–13, 2007. View at Google Scholar
  17. P. Hawk, B. Oser, and W. Summerson, Gastric Analysis. Practical Physiological Chemistry, CRC Press, Toronto, Canada, 1954.
  18. M. Minaiyan, D. N. Ghassemi, and B. Mohammadzadeh, “Anti-ulcer effect of Tripleurospermum disciforme (C.A.Mey) Shultz Bip on pylorus ligated rats,” Research in Pharmaceutical Sciences, vol. 1, pp. 15–21, 2006. View at Google Scholar
  19. O. H. Lowry, N. J. Rosenbrough, A. L. Farr, and R. J. Randall, “Protein measurement with the Folin phenol reagent,” The Journal of Biological Chemistry, vol. 193, no. 1, pp. 265–275, 1951. View at Google Scholar · View at Scopus
  20. G. H. Jeffery, J. Bassett, J. Mendham, and R. C. Denney, Vogel's textbook of quantitative chemical analysis, Longman Scientific and technical publications, London, 5th edition, 1991.
  21. P. Manoharan and S. John, “Anti-ulcer effect of coccinia grandis (linn.) on pylorus ligated (albino) rats,” International Journal of Research and Development, vol. 2, no. 5, pp. 1–9, 2010. View at Google Scholar
  22. K. Sairam, S. Priyambada, N. C. Aryya, and R. K. Goel, “Gastroduodenal ulcer protective activity of Asparagus racemosus: an experimental, biochemical and histological study,” Journal of Ethnopharmacology, vol. 86, no. 1, pp. 1–10, 2003. View at Publisher · View at Google Scholar · View at Scopus
  23. A. Anoop and M. Jegadeesan, “Biochemical studies on the anti-ulcerogenic potential of Hemidesmus indicus R.Br. var. indicus,” Journal of Ethnopharmacology, vol. 84, no. 2-3, pp. 149–156, 2003. View at Publisher · View at Google Scholar · View at Scopus
  24. H. S. Falcao, I. R. Mariath, M. F. F. M. Diniz, L. M. Batista, and J. M. Barbosa-Filho, “Plants of American Continent with anti ulcer activity,” Phytomedicine, vol. 15, pp. 132–146, 2008. View at Google Scholar
  25. A. M. E. El-Arab, M. G. Shenoda, M. H. Eman, and B. A. Azzat, “Effect of dietary honey on intestinal microflora and toxicity of mycotoxins in mice,” BMC Complementary and Alternative Medicine, vol. 6, article 6, 2006. View at Publisher · View at Google Scholar
  26. R. K. Goel, A. Chakrabarti, and A. K. Sanyal, “The effect of biological variables on the anti-ulcerogenic effect of vegetable plantain banana,” Planta Medica, vol. 2, pp. 85–88, 1985. View at Google Scholar · View at Scopus
  27. C. Dixit, R. Leena, and D. Madhu, “Effect of nitric oxide modulators on pylorus-ligation-induced ulcers in the rat,” Pharmacological Research, vol. 39, no. 1, pp. 33–39, 1999. View at Publisher · View at Google Scholar · View at Scopus
  28. J. A. Rodríguez, L. Astudillo, and G. Schmeda-Hirschmann, “Oleanolic acid promotes healing of acetic acid-induced chronic gastric lesions in rats,” Pharmacological Research, vol. 48, no. 3, pp. 291–294, 2003. View at Publisher · View at Google Scholar