Table of Contents
Volume 2011, Article ID 398785, 6 pages
Review Article

Novel Techniques in Endoscopy Are Useful in Evaluating Patients with Ulcerative Colitis

1Department of Gastroenterology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya City, Aichi 466-8550, Japan
2Department of Gastroenterology, Meitetsu Hospital, 2-26-11 Sako, Nishi-ku, Nagoya City, Aichi 451-8511, Japan

Received 30 August 2010; Revised 29 March 2011; Accepted 15 April 2011

Academic Editor: Hajime Kuwayama

Copyright © 2011 Takafumi Ando et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Ulcerative colitis (UC), one of the most common forms of chronic inflammatory bowel disease, is characterized by exacerbations and remissions. Even when conventional colonoscopy suggests remission and a normal mucosal finding, microscopic or histological abnormalities may persist, and relapse may be imminent. Confocal microendoscopy allows histological diagnosis during the endoscopic examination. High-resolution video-magnifying colonoscopy with chromoscopy enables the observation of colorectal mucosal pit patterns and prediction of the probability of subsequent disease relapse in patients in remission. Endoscopic ultrasonography provides an immediate and accurate evaluation of the health status of the colonic wall without the need to wait for histological results and provides an indication of the efficacy of treatment. These novel endoscopic techniques are useful for the evaluation of disease activity and the efficacy of treatment in patients with UC and the prediction of relapse.