Gastroprotective Efficacy of Coenzyme Q10 in Indomethacin-Induced Gastropathy: Other Potential Mechanisms
Figure 1
Effect of 40, 200, and 400 mg/kg coenzyme Q10 (CoQ10-40, -200, and -400; p.o.) as well as 3, 10, 20, and 30 mg/kg pantoprazole (PANTO-3, -10, -20, and -30; p.o.) on gastric volume (a), titratable acidity (b), and acid output (c) in indomethacin-induced (INDO; 20 mg/kg, i.p.) gastric injury. Values are means ± SEM of 6–9 rats; comparisons were carried out using one-way ANOVA followed by Student-Newman-Keuls Multiple Comparisons Test, . As compared to control (CONT) (*); INDO (@); PANTO-10 ($), -20 (#), and -30 (•); CoQ10-200 (†) and -400 (‡).
