Antioxidant Capacity, Cytoprotection, and Healing Actions of the Leaf Aqueous Extract of Ocimum suave in Rats Subjected to Chronic and Cold-Restraint Stress Ulcers
Macromorphological presentation of chronic acetic acid-induced gastric ulcers (ulcers are located on the right half of each photo, (b)–(g)). (a) Healthy control rat. (b) Group 1 (ulcerated rats sacrificed 4 days after acetic acid ulcer induction), showing a deep large ulcer (about 81 mm2), with raised edges and sclerous interior. (c) Group 2 (ulcerated rats given vehicle for 14 days following ulcer induction). (d)–(f) Groups 3, 4, and 5 ulcerated rats treated with 125, 250, and 500 mg/kg bw of extract, respectively, for 14 d after day 4 of ulcer establishment. (g) Positive control rat given ranitidine (50 mg/kg bw) for 14 d following ulcer establishment.