Review Article

Chronic Leg Ulcers: Epidemiology, Aetiopathogenesis, and Management

Table 4

Common lower extremity ulcers [25, 26].

Ulcer typeGeneral characteristicsPathophysiologyClinical features

VenousMost common type; women affected more than men;
often occurs in older persons
Venous hypertensionShallow, painful ulcer located
over bony prominences,
particularly the gaiter area
(over medial malleolus);
granulation tissue and fibrin
present
Associated findings
include edema, venous
dermatitis, varicosities, and
lipodermatosclerosis

ArterialAssociated with cardiac or cerebrovascular disease;
patients may present with claudication, impotence, and pain in distal foot; concomitant with venous disease in up to 25 percent of cases
Tissue ischemiaUlcers are commonly
deep, located over bony
prominences, and round or
punched out with sharply
demarcated borders; yellow
base or necrosis; exposure of
tendons
Associated findings include
abnormal pedal pulses, cool
limbs, femoral bruit, and
prolonged venous filling time

NeuropathicMost common cause of
foot ulcers, usually from
diabetes mellitus
Trauma, prolonged
pressure
Usually occurs on plantar
aspect of feet in patients
with diabetes, neurologic
disorders, or Hansen disease

PressureUsually occurs in patients
with limited mobility
Tissue ischemia and
necrosis secondary
to prolonged
pressure
Located over bony
prominences; risk factors
include excessive moisture
and altered mental status